Related Experiment Video
Updated: May 20, 2026

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
Published on: April 18, 2025
Predicting Sensory Block Level in Caudal Anesthesia Based on Sacral Canal Anatomical Parameters and Height:
Zhengying Li1, Haixuan Wu1, Simin Zhang1
1Department of Anesthesiology, Shenshan Medical Center, Memorial Hospital of Sun Yat-Sen University, Shanwei, Guangdong, People's Republic of China.
Background:
Caudal block in clinical practice relies on empirical drug administration without reliable prediction of anesthetic level, thereby limiting its application. This study aimed to develop a predictive model for sensory block level based on sacral canal anatomical factors and patient characteristics.
Methods:
A total of 132 patients undergoing elective anal surgery with caudal block were included. Ultrasound measured anatomical parameters (the width of the base of the sacrum (BSW), the anterior-posterior diameter of the sacral hiatus at its apex (SHAP), the anterior-posterior diameter of the sacral hiatus at the first segment inferior to the apex (SHFSIA-AP), the length of the sacral hiatus in the sagittal plane (SHLS) and demographic data (age, gender, height, weight) were collected. Sensory block level was categorized into five ordinal grades. Multivariable ordinal logistic regression identified independent predictors, with variance inflation factor (VIF) assessing multicollinearity and Brant test verifying proportional odds assumption. Model performance was evaluated via concordance index (C-index) and Lipsitz test, with internal validation performed using bootstrapping with 1000 resamples, and a nomogram was constructed.
Results:
Univariable analysis showed SHAP, SHLS, SHFSIA-AP, height, age, gender, and weight correlated with sensory block level (P<0.05). Final independent predictors were SHAP, SHLS, and height. No multicollinearity (VIF<5) and valid proportional odds assumption (Brant test P=0.36) were confirmed. The model had good predictive performance (C-index=0.881, 95% CI [0.809-0.953]) and fit (Lipsitz test P=0.49), with the nomogram visualizing probabilities of each block level category.
Conclusion:
This study identified SHAP, SHLS, and height as predictors for caudal block sensory level. The nomogram enables individualized, precise drug administration, shifting the technique from experience-based to precision prediction.
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...