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Updated: May 20, 2026

Transcranial Direct Current Stimulation for Online Gamers

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Problematic Internet Use in Frontotemporal Dementia: A Case Series.

Daniele Urso¹, Giuseppe Volpe^1,2, Agnese Valguarnera^1,2

¹Center for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari "Aldo Moro", "Pia Fondazione Cardinale G. Panico", Tricase, Italy.

Annals of Clinical and Translational Neurology

|May 19, 2026

Summary

Problematic internet use (PIU) is significantly more common in frontotemporal dementia (FTD) patients than in Alzheimer's dementia patients. This finding highlights PIU as a potential behavioral marker for FTD diagnosis and management.

Keywords:

frontotemporal dementia online addictions problematic internet use

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Area of Science:

Neuroscience
Behavioral Science
Gerontology

Background:

Frontotemporal dementia (FTD) presents with diverse behavioral changes.
Problematic internet use (PIU) is an emerging concern in behavioral disorders.
Distinguishing FTD from other dementias like Alzheimer's dementia (AD) is clinically important.

Purpose of the Study:

To investigate the prevalence of PIU in FTD patients.
To compare PIU rates between FTD, mild cognitive impairment (MCI), and AD cohorts.
To identify PIU as a potential behavioral feature of FTD.

Main Methods:

Cross-sectional study comparing patient groups.
Assessment of problematic internet use behaviors.
Statistical analysis to compare PIU prevalence.

Main Results:

PIU was identified in 22.9% of FTD patients.
Only 0.8% of AD patients exhibited PIU (p < 0.001).
Compulsive behaviors included social media, gaming, and online shopping.

Conclusions:

PIU is significantly more prevalent in FTD than in MCI and AD.
PIU may serve as an emerging behavioral indicator for FTD.
Recognizing digital behaviors can aid FTD diagnosis and management.