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Assessing Unilateral Arm Lymphedema Status Using Interarm Tissue Dielectric Constant Ratios.

H N Mayrovitz1

  • 1Department of Medical Education, Dr. Kiran Patel College of Allopathic Medicine, Nova Southeastern University, Florida, USA.

Lymphology
|May 19, 2026
PubMed
Summary
This summary is machine-generated.

Early detection of breast cancer-related lymphedema is crucial. This study establishes a threshold for the tissue dielectric constant (TDC) ratio in healthy women to aid in early lymphedema diagnosis.

Keywords:
Arm lymphedema thresholdsBCRLBreast cancer-related lymphedemaLymphedema detectionTDCTissue dielectric constant

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Area of Science:

  • Biomedical Engineering
  • Oncology
  • Medical Diagnostics

Background:

  • Early-stage lymphedema detection post-breast cancer treatment is vital for intervention.
  • Quantitative methods assessing excess tissue fluid are key for lymphedema diagnosis.
  • Tissue dielectric constant (TDC) ratio is a promising quantitative criterion.

Purpose of the Study:

  • To establish a reliable interarm TDC ratio threshold for diagnosing arm lymphedema.
  • To provide comprehensive reference values for clinical application in lymphedema assessment.

Main Methods:

  • Collected data from 403 healthy women across a wide age and BMI range.
  • Calculated the ratio of highest to lowest forearm TDC values (β).
  • Analyzed the distribution of β and determined thresholds using mean + 2.0, 2.5, and 3.0 standard deviations.

Main Results:

  • The distribution of the interarm TDC ratio (β) was analyzed in healthy women.
  • Estimated thresholds for lymphedema ranged from approximately 1.15 to 1.20.
  • Only 0.74% of healthy cases exceeded a β value of 1.20; age and BMI did not affect β.

Conclusions:

  • The established interarm TDC ratio thresholds provide a quantitative basis for early lymphedema detection.
  • These reference values can assist clinicians in identifying lymphedema in at-risk patients.
  • The findings support the use of TDC ratio as a sensitive and reliable diagnostic tool.