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Updated: May 20, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Residents versus experts in interpreting standard Scheimpflug imaging for the diagnosis of keratoconus
Sadiq Said1,2, Frank Blaser1, Dmitri Artemiev3
1Department of Ophthalmology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Abstract:
PurposeTo evaluate the diagnostic performance of final-year ophthalmology residents in classifying keratoconus using standard Scheimpflug corneal tomography and to compare their accuracy to that of experienced corneal specialists.DesignProspective, investigator-initiated, multicenter observational study.MethodsFive final-year residents assessed 1,239 anonymized Pentacam HR (Oculus GmbH, Germany) quad-map outputs, categorized as normal, suspect keratoconus, or keratoconus, previously obtained from 620 pediatric patients in a prior population-based imaging study. Two corneal experts independently established the reference standard. Residents rated their diagnostic confidence using Likert scales. Agreement was quantified using Cohen's kappa (κ) and Fleiss's κ.ResultsResident-to-expert agreement ranged from Cohen's κ = 0.031 to 0.324 (slight to fair). Overall inter-rater reliability across all raters was slight, Fleiss's κ = 0.088. Four residents rated their diagnostic skill as neutral; one rated it as poor. Self-assessed competence relative to peers was rated as neutral by three residents and good by two.ConclusionsFinal-year ophthalmology residents showed limited agreement with expert graders when interpreting Scheimpflug images. The alignment between self-assessed confidence and measured diagnostic performance highlights a potential educational gap in image-based diagnosis of ectatic corneal disease. These findings support the need for competency-based curricular enhancements, including image interpretation benchmarks, expert-guided calibration sessions, and simulation-based learning modules, aiming to improve diagnostic accuracy and support earlier detection of keratoconus. Further multicenter studies are needed to validate these results and guide national and international training strategies.
