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Related Concept Videos

RNA Editing02:23

RNA Editing

RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
Base Excision Repair01:54

Base Excision Repair

One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
Fixing Double-strand Breaks02:04

Fixing Double-strand Breaks

The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
Fixing Double-strand Breaks02:04

Fixing Double-strand Breaks

The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
Affinity and Avidity01:41

Affinity and Avidity

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Related Experiment Video

Updated: May 21, 2026

Foreign Accent and Forensic Speaker Identification in Voice Lineups: The Influence of Acoustic Features Based on Prosody
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Foreign Accent and Forensic Speaker Identification in Voice Lineups: The Influence of Acoustic Features Based on Prosody

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EVA: Editing for Versatile Alignment against Jailbreaks.

Yi Wang, Hongye Qiu, Yue Xu

    IEEE Transactions on Pattern Analysis and Machine Intelligence
    |May 19, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Large Language Models (LLMs) and Vision Language Models (VLMs) are vulnerable to jailbreaks. A new method, EVA, precisely edits model neurons to enhance safety without harming performance.

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    Last Updated: May 21, 2026

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    Area of Science:

    • Artificial Intelligence
    • Machine Learning Security
    • Natural Language Processing

    Background:

    • Large Language Models (LLMs) and Vision Language Models (VLMs) exhibit advanced capabilities but are susceptible to jailbreaking attacks.
    • Existing defenses like safety fine-tuning or external filters can be computationally expensive and compromise model utility.
    • These methods often lead to a safety-utility trade-off, negatively impacting performance on benign tasks.

    Purpose of the Study:

    • To introduce EVA (Editing for Versatile Alignment against Jailbreaks), a novel framework for safety alignment using direct model editing.
    • To address the limitations of current safety measures in LLMs and VLMs, specifically computational overhead and the safety-utility trade-off.
    • To provide a precise and efficient solution for post-deployment safety alignment against jailbreaking attacks.

    Main Methods:

    • EVA reframes safety alignment as a knowledge correction task, focusing on precise edits rather than extensive retraining.
    • The framework identifies and surgically edits specific neurons responsible for susceptibility to harmful instructions.
    • It ensures that the vast majority of the model's parameters remain unchanged, preserving general reasoning capabilities.

    Main Results:

    • EVA effectively neutralizes harmful behaviors by localizing updates to specific neurons.
    • Experiments show EVA outperforms existing methods in mitigating jailbreaks across both LLMs and VLMs.
    • The proposed method demonstrates a precise and efficient approach to safety alignment without compromising model performance.

    Conclusions:

    • EVA offers a groundbreaking approach to safety alignment in LLMs and VLMs through direct model editing.
    • The framework successfully mitigates jailbreaking vulnerabilities while preserving the model's utility and general capabilities.
    • EVA presents a promising, efficient, and precise solution for enhancing AI safety in deployed models.