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Initial Symptom Duration Among Vulnerable Dialysis Patients Hospitalized for Long-Term Care Correlates With
Takayuki Hirai1, Masataka Banshodani2, Yusuke Kawai2
1Kidney Disease and Dialysis, Akane-Foundation, Ajina Tsuchiya Hospital, Hatsukaichi, Japan.
Introduction:
Among vulnerable dialysis patients, initial symptom duration of coronavirus disease 2019 (COVID-19) has not been investigated extensively.
Methods:
We analyzed 153 dialysis patients with COVID-19 in a long-term care hospital between February 2022 and August 2023. We investigated the association between the delayed resolution of the initial symptoms (≥ 6 days), including fever or upper respiratory symptoms, and worse outcomes. These outcomes were defined as either a decrease in the Geriatric Nutritional Risk Index of ≥ 3.6% at 3 months after onset, or all-cause death within 3 months.
Results:
The duration of the initial symptoms was associated with worse outcomes. This association remained significant after adjustment for patient background, COVID-19 severity, C-reactive protein levels at onset, vaccination, and antiviral therapy, using multivariate analysis.
Conclusion:
The duration of the initial symptoms may be a useful indicator for predicting the poor prognosis, including nutritional deterioration after COVID-19, among vulnerable dialysis patients.
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