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Managing, Analyzing and Sharing Research Data with Gen3 Data Commons
Craig Barnes1, Kyle Burton1, Michael S Fitzsimons1
1Center for Translational Data Science University of Chicago, Chicago, Illinois, USA.
Scientific Data
|May 19, 2026
Summary
Gen3 is an open-source data platform for creating data commons, enabling research communities to manage, analyze, and share data. It automatically generates data portals and FAIR APIs for seamless data access and interoperability.
Area of Science:
- Biotechnology
- Bioinformatics
- Data Science
Background:
- Research communities require robust platforms for managing and sharing large datasets.
- Existing data platforms often lack standardization and interoperability.
- The need for cloud-based solutions to facilitate data commons creation is growing.
Purpose of the Study:
- To introduce Gen3, an open-source data platform for building data commons.
- To highlight Gen3's capabilities in data management, analysis, and sharing.
- To emphasize Gen3's role in fostering interoperability within research ecosystems.
Main Methods:
- Gen3 utilizes a data model to autogenerate a data portal for data exploration.
- It provides a separate portal for data submission into the data commons.
- Gen3 exposes FAIR APIs for programmatic data access.
- The platform is built on standards-based software services for interoperability.
Main Results:
- Gen3 has been successfully implemented to build over 30 data commons globally.
- The platform facilitates the creation of user-friendly data portals.
- FAIR APIs enable efficient and standardized data access.
- Gen3's architecture supports integration with other data platforms.
Conclusions:
- Gen3 offers a scalable and flexible solution for establishing data commons.
- The platform promotes data sharing and collaboration among research communities.
- Gen3's standards-based approach enhances data interoperability and future-proofing.
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