Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 21, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

Probabilistic pathways from chronic pain to suicidal ideation in Qatar: a Bayesian-Network study.

Aisha Al-Khinji1, Dhafer Malouche2

  • 1College of Medicine, Qatar University, Doha, Qatar. aalkhinji@qu.edu.qa.

Journal of Translational Medicine
|May 20, 2026
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Directional Symptom Dependencies in Multiple Sclerosis and Parkinson's Disease: A Comparative Bayesian Network Analysis.

Journal of multidisciplinary healthcare·2026
Same author

Hematological abnormalities in clinically diagnosed non-alcoholic steatohepatitis: prevalence, clinical correlates, and fibrosis risk in a case-control study from Qatar.

Frontiers in medicine·2026
Same author

NOTCH1 mutation status as a prognostic biomarker in T-cell acute lymphoblastic leukemia: a systematic review and meta-analysis.

BMC cancer·2025
Same author

Automated Detection and Grading of Renal Cell Carcinoma in Histopathological Images via Efficient Attention Transformer Network.

Medical sciences (Basel, Switzerland)·2025
Same author

Immune checkpoint inhibitors in pancreatic adenocarcinoma: a systematic review and meta analysis of clinical outcomes.

Frontiers in oncology·2025
Same author

Modeling chronic pain interconnections using Bayesian networks: insights from the Qatar Biobank study.

Frontiers in pain research (Lausanne, Switzerland)·2025

This study mapped probabilistic links between chronic pain, mental health, and suicidal thoughts in Qatar. Self-regret and psychomotor changes were strongly associated with suicidal ideation, highlighting key targets for integrated screening.

Area of Science:

  • Epidemiology
  • Mental Health Research
  • Computational Psychiatry

Background:

  • Chronic pain is linked to increased risk of depressive, anxiety, and suicidal symptoms.
  • Understanding these associations in Middle Eastern populations is limited.
  • This study addresses the gap by examining probabilistic links in Qatari adults.

Purpose of the Study:

  • To map probabilistic interdependencies between chronic pain, mental health symptoms, and demographics in Qatari adults.
  • To identify factors associated with suicidal thoughts.
  • To inform integrated screening and intervention strategies.

Main Methods:

  • Utilized questionnaire data from 2363 Qatari adults (Qatar Biobank).
  • Employed data-driven Bayesian Network (BN) modeling with hill-climbing and BIC scoring.
Keywords:
Bayesian NetworksChronic painCross-sectional studyDepression and anxietyMental-health comorbidityProbabilistic graphical modellingQatar BiobankSuicidal ideation

More Related Videos

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
07:08

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Published on: September 29, 2021

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
09:00

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Published on: July 7, 2023

Related Experiment Videos

Last Updated: May 21, 2026

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
07:08

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Published on: September 29, 2021

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams
09:00

Quantifying Pain Location and Intensity with Multimodal Pain Body Diagrams

Published on: July 7, 2023

  • Constrained BN with domain knowledge and validated arc stability via bootstrap resampling.

    • Main Results:

    • Identified 38 stable directed edges in the BN, revealing complex associations.
    • Self-regret (OR=9.45) and psychomotor change (OR=6.68) were strongest direct associates of suicidal thoughts.
    • A symptom cluster (sleep problems → anhedonia → depression → self-regret) showed strong links to elevated suicide risk; fatigue linked pain and self-regret.

    Conclusions:

    • Bayesian Network modeling elucidated complex, non-linear associations between pain, mental health, and suicidality in Qatar.
    • Cross-sectional design limits causal inference; longitudinal studies are needed.
    • Identified high-risk symptom clusters (self-regret, psychomotor disturbance) as targets for integrated pain-mental health screening, with potential for demographic tailoring.