Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 21, 2026

A Novel Scalp Acupuncture-based Method to Target the Hand Motor Hotspot for Non-invasive Brain Stimulation
07:07

A Novel Scalp Acupuncture-based Method to Target the Hand Motor Hotspot for Non-invasive Brain Stimulation

Published on: December 19, 2025

Electroacupuncture for Motor Recovery in Subacute Stroke: A Randomized Trial Exploring CReST-Related Modulation.

Nan Xia1, Qiongfang Wu1,2, Tangzhu Yang3

  • 1Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Brain and Behavior
|May 20, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fatty diacid-modified FAP-targeted NIR fluorescent probes with modulated pharmacokinetics for enhanced tumor imaging.

The Analyst·2026
Same author

Acacetin-incorporated lipid nanoparticles for inhaled mRNA vaccines.

Nanoscale horizons·2026
Same author

Microbiota, systemic immunity, and extracellular vesicles in stroke: peripheral nodes as therapeutic leverage points.

Journal of neuroinflammation·2026
Same author

Lactate-Depleting Engineered Probiotics Remodel the Tumor Microenvironment and Enhance PD-1 Blockade.

Advanced healthcare materials·2026
Same author

β-Hydroxy Thioether-Derived Ionizable Lipids for Spleen-Tropic mRNA Delivery and <i>In Vivo</i> Chimeric Antigen Receptor T Cell Engineering.

ACS nano·2026
Same author

Dictamnus dasycarpus Turcz. alleviates cholestatic liver injury: orchestrating tissue-divergent extracellular matrix remodeling across the gut-liver axis.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026
Same journal

Voices of Stroke Survivors With Dysphagia: A Roy Adaptation Model-Based Qualitative Analysis.

Brain and behavior·2026
Same journal

Korean Red Ginseng Attenuates Dysfunctions and Modulates Inflammatory and Neuroplasticity Markers in the Harmaline-Induced Model of Essential Tremor.

Brain and behavior·2026
Same journal

Pseudohallucination and Pilocytic Astrocytoma in the Pons.

Brain and behavior·2026
Same journal

Volume Alterations in Thalamic Subnuclei in Parkinson's Disease Dementia and Machine Learning-Based Prediction of Diagnosis and Severity.

Brain and behavior·2026
Same journal

ESTELA-Study: Long-Term Effectiveness and Safety of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies in Real-World Clinical Practice.

Brain and behavior·2026
Same journal

The "Brain's Traffic Map" Reveals Neural Pathways Linked to Coronary Microvascular Dysfunction in Women.

Brain and behavior·2026
See all related articles
This summary is machine-generated.

Electroacupuncture (EA) shows promise for enhancing upper limb motor recovery after stroke by modulating key neural pathways. This study suggests EA may improve motor function and brain network activity in subacute stroke patients.

Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Integrative and Complementary Medicine

Background:

  • Upper limb impairment is a common stroke outcome, with mechanisms of motor recovery not fully understood.
  • Electroacupuncture (EA) is being explored for stroke recovery, but its impact on the corticoreticulospinal tract (CReST) is understudied.
  • Investigating EA's effect on CReST pathways is crucial for understanding stroke rehabilitation.

Purpose of the Study:

  • To investigate the effects of EA on motor recovery in subacute stroke patients.
  • To explore EA's potential modulation of CReST-related pathways.
  • To assess EA's impact on neural activity and motor performance.

Main Methods:

  • Thirty-two subacute stroke patients were randomized into EA or control groups.
Keywords:
corticoreticulospinal tractelectroacupuncturesensorimotor networkstroke rehabilitation

Related Experiment Videos

Last Updated: May 21, 2026

A Novel Scalp Acupuncture-based Method to Target the Hand Motor Hotspot for Non-invasive Brain Stimulation
07:07

A Novel Scalp Acupuncture-based Method to Target the Hand Motor Hotspot for Non-invasive Brain Stimulation

Published on: December 19, 2025

  • Both groups received a two-week rehabilitation program; the EA group received EA at LI4 and LI11 acupoints.
  • Motor function (FMA-UE), spasticity (MAS), motor performance, and neural activity (fNIRS) were assessed.

    • Main Results:

    • The EA group showed significant improvements in upper limb motor function (FMA-UE) and faster reaction times.
    • EA intervention led to increased StartReact incidence and altered anticipatory muscle activations.
    • Functional near-infrared spectroscopy (fNIRS) revealed enhanced sensorimotor network (SMN) activity and improved contralesional SMN connectivity in the EA group.

    Conclusions:

    • EA at LI4 and LI11 appears to be a beneficial adjuvant therapy for upper limb motor recovery in subacute stroke.
    • EA's benefits may stem from modulating CReST pathways and promoting contralesional SMN reorganization.
    • Further research with sham-EA controls is needed to confirm these findings and establish causality.