Establishment of Haemonetics TEG 6s Reference Interval in Healthy Dogs

Area of Science:

• Veterinary Medicine
• Hemostasis and Thrombosis
• Diagnostic Monitoring

Background:

• The TEG 6s, a viscoelastic monitor, is now available for veterinary use.
• Establishing species-specific reference intervals is essential for accurate interpretation.
• This study focused on defining reference intervals for dogs.

Purpose of the Study:

• To establish accurate and acceptable reference intervals for the TEG 6s device in dogs.
• To provide a benchmark for interpreting TEG 6s results in healthy canine populations.

Main Methods:

• Enrolled 130 healthy adult dogs (1-9 years old) with no history of coagulopathies or relevant medications.
• Excluded dogs with abnormal CBC, biochemistry, or physical exams.
• Performed TEG 6s measurements using a Haemonetics Global Hemostasis cartridge with citrated blood samples.

Main Results:

• 123 dogs were included in the final reference interval analysis.
• Established reference intervals for citrated kaolin activated TEG 6s parameters (R, K, alpha angle, maximum amplitude).
• Determined reference intervals for citrated Rapid TEG (CRT) maximum amplitude and reaction time using kaolin-heparinase activation.

Conclusions:

• Successfully established reference intervals for the TEG 6s in a large cohort of normal dogs.
• These reference intervals will aid small animal veterinarians in interpreting results from this newer viscoelastic testing method.
• The data supports the clinical application of TEG 6s in veterinary diagnostics.