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Establishment of Haemonetics TEG 6s Reference Interval in Healthy Dogs
Kaylan Whetstone1, Justin Heinz1, Lonnie E Grantham2
1College of Veterinary Medicine, Texas A&M University, College Station, Texas, USA.
Background:
A thromboelastogram viscoelastic monitor (the TEG 6s) has recently become available for use in veterinary patients. It is therefore necessary to establish reference intervals for the new device in each species where it is employed. This study aimed to establish accurate and acceptable reference intervals for the TEG 6s in dogs.
Objective:
The goal of this study was to establish dog reference intervals (RIs) for the TEG 6s by sampling healthy adult dogs from a variety of breeds.
Methods:
One hundred and thirty dogs (130) aged 1-9 years old were enrolled in this study. Inclusion criteria included healthy adult dogs with no previously reported coagulopathies, no medications that are known to alter coagulation, and normal CBC, biochemistry, and physical exam. TEG 6s measurements were performed using a Haemonetics Global Hemostasis cartridge and citrated blood sample.
Results:
One hundred and twenty-three (123) dogs were included in the TEG 6s RIs. The determined RIs for the citrated kaolin activated were reaction time (R) 2.1-5.6 min, kinetic time (K) 1.1-2.5 min, alpha angle 64.6°-74.9°, and maximum amplitude 47.3-62.0 mm. The determined RIs for citrated Rapid TEG (CRT) maximum amplitude and reaction for the kaolin-heparinase activated were 40.0-59.3 mm and 2.1-5.6 min, respectively.
Conclusions:
RIs were established in a large group of normal dogs, which can assist small animal veterinarians with the interpretation of a newer viscoelastic testing method.
