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Published on: May 10, 2024
Electroacupuncture for treating the cognitive symptoms of Alzheimer's disease: a randomized controlled trial
Ran Li1, Zehao Chen2, Yuhang Jiang2
1Department of Rehabilitation Medicine, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Introduction:
The long-term efficacy of electroacupuncture (EA) in treating cognitive symptoms of Alzheimer's disease (AD) remains unclear, and its time-dependent relationship requires further investigation.
Methods:
Sixty-six patients were allocated to the EA or sham EA group, with stimulation for 20 minutes, for a 24-week treatment period, and were followed-up at 4 weeks. The primary outcome was the mean change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) score. Activities of daily living and behavioral and psychological symptoms were also assessed.
Results:
After 24 weeks of intervention, patients demonstrated significant improvements in ADAS-Cog scores, with sustained benefits observed during the 4-week follow-up period. In addition, improvements were observed in activities of daily living and behavioral and psychological symptoms.
Discussion:
The use of EA as a promising nonpharmacological intervention for AD.
Clinical Trial Registration:
https://www.chictr.org.cn/showproj.html?proj=151275, identifier (ChiCTR2200056329).
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