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Structural and temporal dynamics of pediatric influenza prevention and treatment: a comprehensive bibliometric

Junbin Hong1, Yingying Lin1, Xiaomei Huang1

  • 1Department of Pediatric, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.

Translational Pediatrics
|May 20, 2026
PubMed

Insights

This bibliometric analysis reveals key trends in pediatric influenza research, highlighting immunization and antiviral therapies. Future work should focus on mixed infections and vaccine development for better global control.

Area of Science:

  • Public Health
  • Virology
  • Pediatrics

Background:

  • Pediatric influenza presents a significant global health challenge, necessitating ongoing advancements in vaccines, antivirals, and infection control.
  • The rapid expansion of scientific literature requires systematic synthesis to understand developments in pediatric influenza research.
  • Bibliometric analysis is essential for mapping the evolution, hotspots, and emerging trends in this field.

Purpose of the Study:

  • To conduct a comprehensive bibliometric analysis of research on pediatric influenza prevention and treatment.
  • To identify historical evolution, research hotspots, and emerging trends in the field of pediatric influenza.
  • To examine structural and temporal trends in the scientific literature from 1994 to 2024.

Main Methods:

  • Data were extracted from the Web of Science Core Collection (WoSCC) covering studies from 1994 to 2024.
  • Bibliometric tools including CiteSpace, HistCite, and Alluvial Generator were employed for multidimensional visual analysis.
  • Analyses included publication trends, citation analysis, collaboration networks, keyword clustering, and identification of emergent keywords.

Main Results:

  • Extensive international scientific collaboration was observed in pediatric influenza research.
  • Keyword clustering identified six emerging research subfields, including influenza A, immunization, and oseltamivir.
  • Persistent themes included live attenuated influenza vaccines and neuraminidase inhibitors, with emerging keywords like syncytial virus and acute respiratory illness.

Conclusions:

  • Pediatric influenza research has evolved through three distinct phases, with current focus on COVID-19 interactions, vaccine hesitancy, efficacy, and antiviral resistance.
  • Future research should prioritize understanding mixed infections, developing broad-spectrum vaccines, and innovating antiviral treatments.
  • Strengthening public health interventions and health communication is crucial for improving global pediatric influenza prevention and control.
Abstract

Keywords:
Pediatric influenzabibliometricspreventiontreatmentvisual analysis

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