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Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
Published on: March 26, 2018
Roth Spots As the Initial Manifestation of Accelerated-Phase Chronic Myeloid Leukemia
Meryem Benchekroun1, Salma Hamidi1, Bouchra Fakhir1
1Ophtalmology A, Specialty Hospital of Rabat, Mohamed V University, Rabat, MAR.
Cureus
|May 20, 2026
Summary
Roth spots, white-centered retinal hemorrhages, can signal serious conditions. In one case, these spots were the first sign of accelerated-phase chronic myeloid leukemia, highlighting the importance of eye exams for diagnosing blood disorders.
Area of Science:
- Ophthalmology
- Hematology
- Internal Medicine
Background:
- Roth spots are distinctive white-centered retinal hemorrhages.
- They are often indicative of underlying systemic conditions, including infective endocarditis and hematologic diseases.
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