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Updated: May 21, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Published on: July 14, 2015

PROPTIMUS LIVE: local constrained α-carbon optimization of proteins

Tomáš Svoboda1,2, Michal Mikuš3, Lukáš Bohuš1

  • 1National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Kamenice 5, Brno 625 00, Czech Republic.

Nucleic Acids Research
|May 20, 2026
PubMed
Summary

PROPTIMUS LIVE enhances protein structure precision by optimizing local atom positions using a fast, physics-based force field. This free web service improves data quality for computational chemistry applications.

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Overview