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  3. Acylhydrazone-linked Covalent Organic Frameworks.
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  3. Acylhydrazone-linked Covalent Organic Frameworks.

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Microfluidic-based Synthesis of Covalent Organic Frameworks (COFs): A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface

Published on: July 10, 2017

Acylhydrazone-Linked Covalent Organic Frameworks.

Haipei Shao1,2, Xingyao Ye1, Yongzhi Chen1

  • 1Department of Chemistry, Faculty of Science, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

Journal of the American Chemical Society
|May 20, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

This study introduces acylhydrazone-linked covalent organic frameworks (COFs) synthesized using ketones. These novel COFs exhibit enhanced stability, tunable light emission, and improved water adsorption properties.

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Area of Science:

  • Materials Science
  • Chemistry
  • Nanotechnology

Background:

  • Covalent organic frameworks (COFs) are crystalline porous materials with tunable structures.
  • Aldehydes are commonly used monomers for COF synthesis, but ketones remain underexplored.
  • Acylhydrazone linkages offer potential for novel COF architectures and properties.

Purpose of the Study:

  • To explore ketones as monomers for synthesizing COFs via acylhydrazone linkages.
  • To investigate the impact of reaction conditions on COF crystallinity and porosity.
  • To elucidate the role of acylhydrazone linkages in COF structure and function.

Main Methods:

  • Solvothermal synthesis of COFs using ketones and hydrazides.
  • Screening of reaction parameters (solvent, catalyst, temperature, time).
  • Characterization of COF structure, porosity, and properties.

    • Main Results:

    • Highly crystalline and porous acylhydrazone-linked COFs were successfully synthesized.
    • Acylhydrazone linkages enhanced pore confinement, water adsorption, and adsorption heat.
    • The COFs exhibited improved thermal/chemical stability, π-delocalization, tunable light emission, reduced bandgaps, and enhanced photoconductivity.

    Conclusions:

    • Ketones can be effectively utilized as monomers for COF synthesis, expanding the scope of COF design.
    • Acylhydrazone linkages significantly influence COF structural and functional characteristics.
    • This work presents a new strategy for developing advanced COFs with tailored properties for diverse applications.