A simplified, tier-based method for clinical evaluation of diastolic function
Edgar Argulian1, Sherif F Nagueh2, Julia Grapsa3
1Mount Sinai Morningside, Icahn School of Medicine at Mount Sinai, 1111 Amsterdam Avenue, New York, NY 10025, USA.
European Heart Journal. Cardiovascular Imaging
|May 20, 2026
Summary
This review simplifies assessing left ventricular diastolic function using the 2025 American Society of Echocardiography guidelines. It offers a probabilistic framework for improved clinical interpretation and consistent application in practice.
Area of Science:
- Cardiology
- Echocardiography
- Medical Imaging
Background:
- Assessing left ventricular diastolic function is complex and faces challenges with terminology, load dependence, and integrating discordant echocardiographic parameters.
- Consistent clinical application requires simplification of current assessment methods.
Purpose of the Study:
- To present a simplified, clinically oriented approach to diastolic function assessment based on contemporary imaging guidelines, focusing on the 2025 American Society of Echocardiography recommendations.
- To enhance clinical relevance, interpretive confidence, and consistent application of diastolic function assessment in routine practice.
Main Methods:
- Review of contemporary imaging guidelines for diastolic function assessment, emphasizing the 2025 American Society of Echocardiography recommendations.
- Application of a probabilistic diagnostic framework integrating clinical context, echocardiographic findings, and advanced imaging.
- Discussion of emerging artificial intelligence-based approaches for diastolic dysfunction assessment.
Main Results:
- A simplified, probabilistic framework is proposed for diastolic function assessment.
- Integration of clinical context and advanced imaging improves diagnostic accuracy.
- Artificial intelligence approaches offer potential for enhanced diagnostic and prognostic assessment.
Conclusions:
- The proposed pragmatic approach aims to improve the consistency and confidence in assessing diastolic function in clinical practice.
- Contemporary guidelines and advanced imaging, including AI, are crucial for accurate diastolic function evaluation.
- Simplification of assessment protocols is key for widespread clinical adoption.
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