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Related Experiment Video

Updated: May 22, 2026

Microembossing: A Convenient Process for Fabricating Microchannels on Nanocellulose Paper-Based Microfluidics
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Integration of a Rhodamine-Bromophenol Blue into Portable Paper-Based and Arduino-Assisted Platforms for Selective

Sunbin Choi1, Ramalingam Manivannan1, Palanisamy Jayasudha1

  • 1Department of Advanced Organic Materials Engineering, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejeon, 305-764, South Korea.

Journal of Fluorescence
|May 20, 2026
PubMed
Summary

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This summary is machine-generated.

A new dual-mode chemosensor, BPRH, combines colorimetric and fluorometric sensing with pH indication. It selectively detects Al³⁺, Hg²⁺, and Cu²⁺ ions, showing promise for portable analytical devices.

Area of Science:

  • * Analytical Chemistry
  • * Materials Science
  • * Chemical Sensing

Background:

  • * Development of sensitive and selective chemosensors is crucial for environmental monitoring and biological analysis.
  • * Integrating multiple sensing modalities (colorimetric, fluorometric, pH) into a single molecule simplifies detection and broadens applications.
  • * Existing sensors often lack selectivity or require complex instrumentation.

Purpose of the Study:

  • * To design and synthesize a novel dual-mode chemosensor, BPRH, for simultaneous pH indication and metal ion detection.
  • * To evaluate the selectivity and sensitivity of BPRH towards various metal ions and its pH-dependent optical properties.
  • * To explore the practical applicability of BPRH in portable analytical devices.

Main Methods:

Keywords:
Arduino platformFluorescenceOptical sensorSelective colorpH indicator

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  • * Synthesis of BPRH by conjugating a Rhodamine derivative with Bromophenol Blue.
  • * Spectrophotometric and fluorometric analysis to study optical responses to pH and metal ions (Al³⁺, Hg²⁺, Cu²⁺).
  • * Fabrication of paper-based analytical devices and an Arduino-assisted RGB color detection platform for practical testing.

Main Results:

  • * BPRH exhibited a distinct color change from blue to pink under acidic conditions (pH < 3), indicating pH sensitivity.
  • * The chemosensor showed high selectivity for Al³⁺, Hg²⁺, and Cu²⁺, with unique colorimetric responses for each ion.
  • * Al³⁺ and Hg²⁺ significantly enhanced fluorescence, with Al³⁺ showing the strongest response, particularly at physiological pH.
  • * BPRH demonstrated successful application in paper-based devices and an Arduino-assisted platform for rapid, instrument-free detection.

Conclusions:

  • * BPRH is a versatile dual-mode chemosensor with excellent pH-dependent optical behavior and high selectivity for specific metal ions.
  • * The chemosensor's strong fluorescence response and optimal performance at physiological pH make it suitable for biological applications.
  • * Integration with low-cost, portable platforms like paper-based devices and Arduino systems enables rapid, on-site quantitative analysis.