Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase01:11

Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase

Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tuning Second-Order Nonlinear Optical Properties via Electronic Interaction Engineering: Distinct Roles of Nonconjugation, σ-π Conjugation, and Intramolecular Charge Transfer in Chalcogen‑Functionalized Closo-Carborane Hybrids.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same author

Dual-hit cystic kidneys: ADPKD with de novo HNF1B deletion.

Kidney international·2026
Same author

Relationship of subclinical lung injury to chronic airway inflammation in spinocerebellar ataxia type 3.

Orphanet journal of rare diseases·2026
Same author

Sulfated <i>Pelvetia siliquosa</i> Polysaccharides Attenuate Pyroptosis via NF-κB Pathway Inhibition Against Calcium Oxalate Stone Formation.

Marine drugs·2026
Same author

Screening for genetic kidney diseases in a dialysis cohort via exome sequencing.

Clinical kidney journal·2026
Same author

Peripheral metabolic profiles in spinocerebellar ataxia type 3: Features and genotype-phenotype links.

Parkinsonism & related disorders·2026

Related Experiment Videos

Taurine in Atherosclerosis: A Multitarget Perspective.

Lin-Xi Xie1, Qing-Qi Xu1, Jie-Yao Liu1

  • 1Research Laboratory of Translational Medicine, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China; Department of Clinical Medicine, Hengyang Medical School, University of South China, Hengyang, Hunan, People's Republic of China.

The Journal of Nutrition
|May 20, 2026
PubMed
Summary

Taurine, a sulfur-containing amino acid, offers cardiovascular protection by regulating lipid metabolism and reducing inflammation. This dietary supplement may help prevent atherosclerosis (AS) and improve gut health.

Keywords:
atherosclerosiscardiovascular diseasegut microbiotalipid metabolismoxidative stresstaurine

Related Experiment Videos

Area of Science:

  • Biochemistry
  • Cardiovascular Science
  • Nutritional Science

Background:

  • Atherosclerosis (AS) is a major cause of vascular events like stroke and heart attack.
  • Taurine is a conditionally essential amino acid involved in physiological processes.
  • Taurine exhibits multifaceted roles in cardiovascular health and disease prevention.

Purpose of the Study:

  • To investigate the protective role of taurine against atherosclerosis.
  • To explore taurine's mechanisms in regulating lipid metabolism, platelet function, and vascular cell proliferation.
  • To examine taurine's antioxidant effects, vasodilation properties, and endothelial repair capabilities.

Main Methods:

  • Review of current scientific literature on taurine and atherosclerosis.
  • Analysis of taurine's impact on lipid metabolism and platelet aggregation.
  • Evaluation of taurine's effects on vascular smooth muscle cell proliferation and endothelial function.

Main Results:

  • Taurine regulates lipid metabolism and reduces platelet activation.
  • It inhibits vascular smooth muscle cell proliferation and exhibits antioxidant properties.
  • Taurine promotes vasodilation, endothelial repair, and interacts with the gut microbiome.

Conclusions:

  • Taurine is a promising cardiovascular protective agent against atherosclerosis.
  • Its supplementation can enhance intestinal and cardiovascular health.
  • Taurine may reduce the risk of atherosclerosis through various physiological mechanisms.