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Related Experiment Video

Updated: Jun 18, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

Revitalization in Traumatized Immature Teeth With External Inflammatory Root Resorption: A Systematic Review.

Ghina Al Khourdaji1, Timothy Fasham2,3, Samantha Elbhar1

  • 1Department of Restorative Dentistry, Pitié Salpétrière Hospital (AP-HP), Paris, France.

Dental Traumatology : Official Publication of International Association for Dental Traumatology
|May 21, 2026
PubMed
Summary

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Revitalization shows promise for treating traumatized immature teeth with external inflammatory root resorption (EIRR). This treatment achieved a 100% survival rate and 85% success in resolving symptoms and arresting resorption.

Area of Science:

  • Dentistry
  • Regenerative Endodontics
  • Dental Traumatology

Background:

  • External inflammatory root resorption (EIRR) is a complication of dental trauma in immature teeth.
  • Revitalization aims to promote healing and tissue regeneration within the root canal system.
  • Evaluating the efficacy of revitalization for EIRR is crucial for improving treatment outcomes.

Purpose of the Study:

  • To systematically review the literature on the use of revitalization in treating traumatized immature teeth with EIRR.
  • To assess the success rates and biological repair associated with revitalization in these cases.

Main Methods:

  • A systematic literature search was conducted across PubMed, EMBASE, Scopus, and Web of Science.
  • Studies involving revitalization for traumatized immature teeth with EIRR were included.
Keywords:
dental traumaexternal inflammatory root resorptionpulp revitalizationregenerative endodontic procedures

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  • Risk of bias was assessed using Joanna Briggs Institute Critical Appraisal Tools.

    • Main Results:

    • Thirteen studies comprising 20 teeth in 17 patients were analyzed.
    • Revitalization demonstrated a 100% survival rate and 85% success rate.
    • 85% of treated teeth showed resolution of clinical/radiographic signs and arrest of EIRR; root development was unpredictable.

    Conclusions:

    • Revitalization appears to be a promising treatment for biological repair in immature teeth with post-traumatic EIRR.
    • Confirmation of arrested resorption after disinfection is key for successful revitalization.
    • The review's findings are limited by a high proportion of case reports.