Histopathologic outcomes comparison between cold snare polypectomy and cold snare EMR for colorectal polyps: a...

Area of Science:

• Gastroenterology
• Endoscopic Surgery
• Colorectal Cancer Prevention

Background:

• Colorectal polyps measuring 6-15 mm require effective and safe removal techniques.
• Cold snare techniques are increasingly used, but direct comparisons are needed.
• Evaluating cold snare polypectomy (CSP) versus cold snare endoscopic mucosal resection (CS-EMR) is crucial for optimizing patient outcomes.

Purpose of the Study:

• To compare the efficacy and safety of CSP and CS-EMR for colorectal polyps (6-15 mm).
• To assess key outcomes including complete resection rates and intraprocedural bleeding.

Main Methods:

• A single-blind, randomized-controlled trial involving 214 patients with solitary colorectal polyps.
• Patients were randomized to either CSP or CS-EMR.
• Outcomes included pathologic complete resection, muscularis mucosae coverage, submucosal coverage, residual lesions, bleeding, and perforation rates.

Main Results:

• Both CSP and CS-EMR achieved comparable pathologic complete resection rates (91% vs 89%).
• No significant differences were observed in submucosal or residual lesion coverage rates.
• CSP demonstrated a significantly lower intraprocedural bleeding rate (25% vs 44%).

Conclusions:

• CSP and CS-EMR exhibit similar efficacy and safety for resecting 6-15 mm colorectal polyps.
• CSP is associated with reduced intraprocedural bleeding compared to CS-EMR.
• CSP is recommended as the preferred method due to its cost-effectiveness and operational efficiency.