A rare presentation of male breast atypical papillary lesion

Papillary breast lesions are a heterogeneous group of lesions with epithelial origin, composed predominantly of papillae, and they are particularly rare in men. Atypical papillary lesions are rare epithelial tumors, characterized by cytologic or architectural features that are not clearly benign but may fall short of definitive malignancy. Herein, we present a case of a 51-year-old man admitted with painless, hemorrhagic discharge from the left nipple. Ultrasonography revealed an intraductal solid mass in the left breast, along with mild bilateral gynecomastia. Core needle biopsy (CNB) subsequently confirmed an atypical papillary lesion. This case highlights the importance of imaging and tissue biopsy in establishing an accurate diagnosis, due to their wide spectrum of histological presentations from benign to malignant, which should be well differentiated.