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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...
Antiepileptic Drugs: Potassium Channel Activators01:20

Antiepileptic Drugs: Potassium Channel Activators

Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

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Related Experiment Video

Updated: May 22, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Epi-STEP: A multidisciplinary transition model for patients with epilepsy.

Valentina Giobbe1, Giorgia Mulè1, Martina Paola Zanaboni2

  • 1Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.

Methodsx
|May 21, 2026
PubMed
Summary

The Epi-STEP protocol offers a multidisciplinary approach to support adolescents with epilepsy transitioning to adult care, addressing medical, psychological, and social needs for improved outcomes.

Keywords:
AdolescentCaregiver perspectiveEpilepsyPatient perspectiveProtocolQuality of lifeTransitionUnmet needs

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A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

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Last Updated: May 22, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

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09:41

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery

Published on: May 20, 2016

Area of Science:

  • Neurology
  • Adolescent Medicine
  • Healthcare Management

Background:

  • Epilepsy is a common childhood neurological disorder, with many cases persisting into adulthood.
  • Transitioning from pediatric to adult care is crucial but often lacks structured support.
  • Existing epilepsy centers frequently lack formal transition programs, highlighting a need for standardization.

Purpose of the Study:

  • To evaluate the Epi-STEP protocol, a multidisciplinary transition model for young adults with epilepsy.
  • To assess the usefulness of this transition process in preparing patients for adult care.
  • To examine the psychosocial well-being of patients and their caregivers during the transition.

Main Methods:

  • A monocentric observational study involving patients aged 16+ with epilepsy.
  • Data collection at three time points: pre-transition (T0), start of adult care (T1), and 12-month follow-up (T2).
  • Utilized standardized instruments and ad-hoc questionnaires for patients, caregivers, and healthcare professionals.

Main Results:

  • The study aims to evaluate the utility of the transition process.
  • Key metrics include transition readiness and psychosocial well-being.
  • Findings will inform targeted interventions to enhance patient and family support.

Conclusions:

  • The Epi-STEP protocol provides a holistic care pathway for adolescents with epilepsy.
  • This model supports medical, psychological, and social needs during the transition.
  • The approach may be adaptable to other chronic conditions requiring structured transition regimens.