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Polysomnographic Characteristics and Sleep Disorders in Pediatric Moyamoya Arteriopathy

Kantisa Sirianansopa1,2, Reshma Amin2,3,4, Jackie Chiang2,3

  • 1Division of Pulmonary Medicine, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Nature and Science of Sleep
|May 21, 2026
PubMed

Insights

Pediatric patients with Moyamoya arteriopathy (MMA) often experience sleep fragmentation and daytime fatigue. Further research is needed to confirm these findings in children with MMA.

Area of Science:

  • Neurology
  • Sleep Medicine
  • Pediatrics

Background:

  • Moyamoya arteriopathy (MMA) is a rare cerebrovascular disorder.
  • Sleep disturbances are increasingly recognized in pediatric neurological conditions.

Purpose of the Study:

  • To characterize polysomnographic findings in pediatric patients with MMA.
  • To describe sleep-related symptoms in this cohort.

Main Methods:

  • Retrospective case series of 11 pediatric patients with MMA undergoing polysomnography (PSG).
  • Review of clinical, demographic, genetic, and sleep data, including PSG and MSLT.
  • Data collected between 2014 and 2024.

Main Results:

  • Sleep fragmentation was prevalent (90.9%) on PSG.
  • No significant sleep-disordered breathing was observed.
  • A trend toward shorter REM latency and frequent daytime fatigue (54.5%) were noted.

Conclusions:

  • Pediatric patients with MMA commonly exhibit sleep fragmentation and daytime fatigue.
  • Findings suggest potential sleep disturbances in MMA, warranting further investigation.
  • Small sample size necessitates cautious interpretation and future prospective studies.
Abstract

Keywords:
REM latencyhypersomnolencemoyamoya arteriopathypediatricpolysomnographysleep fragmentation

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