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Updated: May 22, 2026
08:21
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ST-Segment Elevation in a Patient With Vocal Cord Cancer: A Great Mimicker
Luis Rene Puglla-Sanchez1, Javier Mario Valcuende Rosique1, David Mendez Portuburu1
1Department of Cardiology, Clinico Lozano Blesa University Hospital, Zaragoza, Spain.
JACC. Case Reports
|May 21, 2026
Summary
Cardiac metastasis can mimic heart attacks, presenting a pseudoinfarction pattern. Early echocardiography is key to identifying tumor infiltration versus acute coronary syndromes, avoiding unnecessary procedures.
Area of Science:
- Cardiology
- Oncology
- Medical Imaging
Background:
- Cardiac metastasis is a rare condition.
- It can mimic ST-segment elevation myocardial infarction (STEMI), a pseudoinfarction pattern.
- This occurs due to persistent injury currents at the tumor-myocardium interface.
Purpose of the Study:
- To highlight a case of cardiac metastasis mimicking STEMI.
- To emphasize the importance of recognizing this pseudoinfarction pattern.
- To differentiate malignant injury currents from acute coronary syndromes.
Main Methods:
- Case presentation of a 58-year-old man with laryngeal carcinoma.
- Clinical evaluation including chest pain, ECG, and troponin levels.
- Diagnostic imaging: bedside echocardiography and positron emission tomography-computed tomography (PET-CT).
Main Results:
- Patient presented with pleuritic chest pain and ST-segment elevation.
- Echocardiography revealed a right ventricular mass.
- PET-CT confirmed extensive neoplastic infiltration of the myocardium.
- Diagnosis of cardiac metastasis mimicking STEMI was established.
Conclusions:
- Persistent ST-segment elevation in oncology patients warrants suspicion for myocardial tumor infiltration.
- Multimodality imaging, especially bedside echocardiography, is crucial.
- Differentiating tumor infiltration from acute coronary syndromes avoids futile invasive interventions and guides therapy.
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