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Updated: May 23, 2026

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
07:30

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New chalcogen-optimized 1,3,5-triazines as dual 5-HT6R/FAAH modulators: A versatile approach to neurodegenerative

Kinga Czarnota-Łydka1, Katarzyna Kucwaj-Brysz2, Agnieszka Cios3

  • 1Chair of Chemical Technology and Biotechnology of Drugs, Jagiellonian University, Medical College, Medyczna 9, PL, Krakow, 30-688, Poland; School of Medical and Health Sciences, Jagiellonian University Medical College, św. Łazarza 15, Krakow, 31-530, Poland.

European Journal of Medicinal Chemistry
|May 21, 2026
PubMed
Summary

New triazine compounds show promise for Alzheimer's disease treatment by targeting multiple pathways. Compound 4c demonstrated significant neuroprotection and improved memory in vivo, offering a potential disease-modifying therapy.

Keywords:
1,3,5-Triazine5-HT(6)RAlzheimer's diseaseFAAHNeuroprotectionSelenocompounds

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