Related Experiment Video
Updated: May 23, 2026

Mouse Round Spermatid Injection
Published on: January 26, 2024
Comparison of cost for conventional embryo transfer versus intracytoplasmic sperm injection
1Reproductive Management LLC, 55336 North Co. Rd 3 Fort Collins Co 80524, USA.
Background:
There are obvious practical advantages of both conventional ET and ICSI. One question that has not been addressed adequately, however, is the relative cost of each procedure and if there is a cost advantage of one over the other.
Aims/Objectives:
The objective of the present study was to obtain additional cost data from clinics and breeding farms that perform both ET and ICSI.
Methods:
A request was sent to 10 clinics that performed either just OPU or OPU/ICSI. These facilities were representative of reproductive specialists located all across the United States. Six clinics provided information on at least 10 ICSI and 10 ET mares.
Results:
In 3/6 clinics the cost of generating an embryo by ICSI was less than the cost of generating an embryo by uterine flushing, nearly the same in one clinic and more than double the cost of generating ICSI embryos in 2 clinics.
Conclusion:
The cost of ICSI embryos can be similar to that for ET embryos if one considers the extra embryos produced by ICSI that are vitrified and stored for transfer at a later time and the facility is producing at least 2.5 embryos/OPU. The client should take into consideration all the factors and then choose the technique that best meets their needs.

