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Related Concept Videos

Muscle Recovery and Fatigue01:24

Muscle Recovery and Fatigue

Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective response...
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Fatigue01:21

Fatigue

Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
Fatigue Strength of Concrete01:22

Fatigue Strength of Concrete

Fatigue, in the context of materials science and engineering, refers to the weakening or failure of a material caused by repeatedly applied loads, even if these loads are below the strength limit of the material. Fatigue strength in concrete is a critical property that influences its durability and longevity. Concrete can fail in two ways due to fatigue. Static fatigue or creep rupture occurs under a constant load or one that increases slowly. The other failure mode is due to cyclical or...

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Related Experiment Video

Updated: May 23, 2026

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse
09:25

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

Published on: May 31, 2016

Mental Fatigue and Resistance Exercise: A Systematic Review and Meta-Analysis Including GRADE Qualification.

Luiz José Frota Solon-Júnior1,2,3, Leonardo de Sousa Fortes4, Gustavo Vasconcelos5

  • 1Federal University of Paraíba, Joao Pessoa, Brazil.

European Journal of Sport Science
|May 21, 2026
PubMed
Summary
This summary is machine-generated.

Mental fatigue (MF) negatively impacts resistance exercise (RE) volume, particularly for multijoint exercises and moderate-intensity loads. This meta-analysis confirms MF

Keywords:
braincognitive effortmental demandphysical exerciseresistance training

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Last Updated: May 23, 2026

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Area of Science:

  • Exercise Physiology
  • Cognitive Neuroscience
  • Sports Science

Background:

  • Mental fatigue (MF) is increasingly studied for its effects on physical performance.
  • Previous meta-analyses require updating due to a rise in relevant randomized controlled trials (RCTs).

Purpose of the Study:

  • To conduct a comprehensive systematic review and meta-analysis on the effects of MF on resistance exercise (RE) performance.
  • To evaluate MF's impact across different subgroups and provide GRADE qualification.

Main Methods:

  • Included RCTs involving healthy participants, cognitive tasks, control conditions, and RE performance measures.
  • Performed random-effects meta-analysis on 14 comparisons from 11 studies (>205 participants).
  • Conducted subgroup analyses based on exercise type, intensity, and training volume.

Main Results:

  • A significant negative effect of cognitive effort on RE volume was found (g = -0.39, p < 0.01).
  • Multijoint exercises showed greater impairment (g = -0.45) than single-joint exercises (g = -0.20).
  • Impairment was larger at moderate-intensity loads (60%-79% 1RM) and high training volumes.

Conclusions:

  • This meta-analysis confirms that mental fatigue negatively impacts resistance exercise volume.
  • Findings suggest specific exercise types, intensities, and volumes are more susceptible to MF.
  • Evidence quality is moderate, warranting cautious interpretation of results.