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Updated: May 23, 2026

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The Lower Body Positive Pressure Treadmill for Knee Osteoarthritis Rehabilitation
Published on: July 22, 2019
Contralateral Knee Alignment Parameters Have Limited Influence on Coronal Alignment Progression Compared With
Kee Soo Kang1, Byung Sun Choi1,2, Hyuk-Soo Han1,2
1Department of Orthopaedic Surgery, Seoul National University Hospital, Seoul, Republic of Korea.
Cartilage
|May 21, 2026
Summary
Bilateral knee alignment concordance was moderate, with contralateral limb having minimal impact on hip-knee-ankle angle progression. Ipsilateral parameters were more influential for knee osteoarthritis progression.
Area of Science:
- Orthopedics
- Radiology
- Biomechanical Engineering
Background:
- Knee osteoarthritis (OA) progression is influenced by lower limb alignment.
- Understanding bilateral lower extremity alignment and its progression is crucial for OA management.
Purpose of the Study:
- To compare alignment parameters in bilateral lower extremities.
- To evaluate the longitudinal effect of the contralateral limb on hip-knee-ankle angle (HKAA).
Main Methods:
- Long-leg radiographs of 3,045 Korean patients were analyzed for knee OA progression.
- Concordance rates of Functional Knee Phenotypes (FKPs) and Coronal Plane Alignment of the Knee (CPAK) were assessed.
- Multivariable linear regressions analyzed the association between contralateral limb parameters and follow-up HKAA.
Main Results:
- Baseline concordance rates for FKPs and CPAK were 41.6% and 53.5%, respectively.
- Follow-up concordance rates for FKPs and CPAK were 35.5% and 55.4%, respectively.
- Contralateral parameters showed limited influence on HKAA progression compared to ipsilateral parameters.
Conclusions:
- Bilateral lower extremity alignment concordance for FKPs and CPAK is moderate.
- Ipsilateral limb parameters are more significant predictors of HKAA progression than contralateral parameters.
- Contralateral limb influence on coronal alignment progression in knee OA is limited.
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