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Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Interpersonal Psychotherapy01:25

Interpersonal Psychotherapy

Interpersonal psychotherapy (IPT) is a structured, time-limited therapeutic approach initially developed to treat depression. It integrates key concepts from psychodynamic, humanistic, and cognitive-behavioral therapies, making it a uniquely eclectic framework. The therapy is rooted in the interpersonal theories of Adolph Meyer and Harry Stack Sullivan, as well as John Bowlby's attachment theory, and focuses on the interplay between interpersonal relationships and emotional well-being.
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Specialized Care Centers and Settings-II01:30

Specialized Care Centers and Settings-II

Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...

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Related Experiment Video

Updated: May 23, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

A 3-Week Intensive Outpatient Program for Patients With Persistent Neuropsychiatric Symptoms After Remote TBI.

Alicia K Vose1, Vaughn E Bryant1,2, Jade Hannan1

  • 1Department of Neurology, University of Florida College of Medicine, Jacksonville.

The Journal of Neuropsychiatry and Clinical Neurosciences
|May 22, 2026
PubMed
Summary
This summary is machine-generated.

Intensive, interdisciplinary rehabilitation significantly improved neurobehavioral and cognitive symptoms in veterans and first responders with TBI. The program also reduced PTSD symptoms and enhanced life satisfaction.

Keywords:
Interdisciplinary CareOutpatient RehabilitationPostconcussion SymptomsPosttraumatic Stress DisorderTraumatic Brain InjuryVeterans

Related Experiment Videos

Last Updated: May 23, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

Area of Science:

  • Neuroscience
  • Psychiatry
  • Rehabilitation Medicine

Background:

  • Persistent postconcussive symptoms and co-occurring conditions are prevalent in veterans and first responders following traumatic brain injury (TBI).
  • Integrated neuropsychiatric rehabilitation programs aim to address the complex, multidomain needs of this population.

Purpose of the Study:

  • To evaluate the effectiveness of a 3-week interdisciplinary intensive outpatient program for veterans and first responders with persistent postconcussive symptoms and co-occurring conditions after remote TBI.
  • To assess changes in neurobehavioral symptoms, cognitive function, mobility, vestibular function, and life satisfaction.

Main Methods:

  • Retrospective cohort study of 128 patients.
  • Utilized patient-reported measures (Neurobehavioral Symptom Inventory [NSI], PTSD Checklist for DSM-5 [PCL-5], Life Satisfaction Questionnaire-11 [LiSat-11]).
  • Included objective assessments: Addenbrooke's Cognitive Examination-III (ACE-III), gait speed, computerized dynamic posturography (Sensory Organization Test [SOT]), and Modified Clinical Test of Sensory Interaction in Balance (mCTSIB).
  • Paired t tests and linear mixed-effects models were used for analysis.

Main Results:

  • Significant reduction in neurobehavioral symptoms (NSI total score decreased by 41%, Cohen's d=1.11).
  • Improvements in cognitive function (ACE-III scores increased by 6.8 points, Cohen's d=1.41).
  • Significant enhancements in gait speed, vestibular function (SOT, mCTSIB), and a decline in PTSD symptom screening (PCL-5) from 51% to 20%.
  • Higher baseline PCL-5 scores correlated with higher NSI scores over time (p<0.001).

Conclusions:

  • Intensive, interdisciplinary neuropsychiatric rehabilitation demonstrates multidomain benefits for veterans and first responders with TBI.
  • Integrated care models show potential for reducing symptom burden and improving cognitive, mobility, vestibular, and life satisfaction outcomes.
  • A strong link exists between posttraumatic stress severity and neurobehavioral symptom burden in this population.