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Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
Epidemiological Investigation of a Tuberculosis Cluster Outbreak at a University - Changsha City, Hunan Province,
Cifu Xie1, Pengliang Yin1, Linxin Song1
1Department of Tuberculosis Prevention and Control, Changsha Center for Disease Control and Prevention, Changsha City, Hunan Province, China.
What Is Already Known About This Topic?:
Tuberculosis (TB) is prone to cause clustered transmission in schools.
What Is Added By This Report?:
Following outbreak, the university conducted terminal disinfection of epidemic sites; however, Mycobacterium tuberculosis was detected (including air conditioner filters and air). Individuals with latent TB infection who receive preventive immunotherapy with Mycobacterium vaccae can develop active TB. Active cases were not identified promptly after preventive treatment, leading to renewed transmission.
What Are The Implications For Public Health Practice?:
Guidelines should add disinfection effectiveness evaluations and cover easily overlooked items, such as air conditioner filters. Follow-up examinations for individuals with LTBI who have completed preventive treatment remain necessary, as they still face a significant risk of developing active TB.
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