Related Experiment Video
Updated: May 23, 2026

13:28
Gradient Strain Chip for Stimulating Cellular Behaviors in Cell-laden Hydrogel
Published on: August 8, 2017
Enabling gradient biomineralization and prestress with a macroscopic matrix: the fish swim bladder for
Bingyu Xue1,2, Junming Wu2, Jiangyu Yi2
1Hubei Longzhong Laboratory, Xiangyang, Hubei, P. R. China. kun.wang@whut.edu.cn.
Materials Horizons
|May 22, 2026
Abstract:
The hierarchical mineralization of bone inspires advanced materials, yet replicating it macroscopically remains challenging. The fish swim bladder (FSB) is a natural collagen scaffold that could bridge this gap. Its bone-like architecture guided gradient biomineralization and intrinsic prestress generation, yielding exceptional mechanical properties. The mineralized FSB enabled bioprocessing-inspired fabrication of high-performance bulk composites.
