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Laser and Energy-Based Device Treatments for Melasma: A Systematic Review and Meta-Analysis of Randomized Controlled

Mutian Ding1, Jia Qi Adam Bai2, Ryan S Q Geng1

  • 1Temerty Faculty of Medicine, University of Toronto, ON, Canada.

Journal of Cutaneous Medicine and Surgery
|May 22, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
laser treatmentmelasmameta-analysisrandomized controlled trialssystematic review

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Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...

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