Progressive Conduction Disease in a Mitochondrial Disorder
Tânia Amaro1, Savia Bueno2, Cinthya Guirão2
1Arrhythmia Unit, Heart Institute (Incor), University of São Paulo Medical School, São Paulo, Brazil; Cardiology Department, Clínica Girassol, Luanda, Angola.
Case Summary:
We describe the case of a 45-year-old man with progressive external ophthalmoplegia and pigmentary retinopathy who was referred for evaluation of a bradyarrhythmia due to exertional dyspnea and fatigue. A baseline electrocardiogram and ambulatory monitoring revealed clinically significant conduction abnormalities.
Take-Home Messages:
In Kearns-Sayre syndrome, conduction abnormalities may progress unpredictably; early permanent pacing should be strongly considered. Consider implantable cardioverter-defibrillator rather than pacemaker alone when additional high-risk features are present.
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