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Interpreting Mitochondrial Bioenergetics in Ischaemia-Reperfusion Injury: Caution on Causality and Methodological

Malaha Ali1

  • 1Department of Medicine, Liaquat University of Medical and Health Sciences, Hyderabad, Pakistan. malaha.ali.rana48@gmail.com.

Cardiovascular Drugs and Therapy
|May 22, 2026
PubMed
Abstract

No abstract available in PubMed .

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A single mitochondrion is a bean-shaped organelle enclosed by a double-membrane system. The outer membrane of mitochondria is smooth and contains many porins - the integral membrane transporters. Porins enable free diffusion of ions and small uncharged molecules through the outer mitochondrial membrane but limit the transport of molecules larger than 5000 Daltons. Further, the outer mitochondrial membrane forms a unique structure called membrane contact sites with other subcellular organelles,...

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