A Transdiagnostic Group Intervention for Managing Depression and Anxiety in Older Adults: A Prospective Single-Arm...

This study explored the preliminary efficacy and feasibility of a transdiagnostic group intervention integrating the Unified Protocol (UP) and Process-Based Therapy (PBT) for older adults with comorbid depression and anxiety.

A prospective single-arm pre - post and follow - up study was conducted with 36 older adults (Mean Age = 68.4, SD = 2.8, Range = 60-71). Assessments (PHQ-9, GAD-7, and WHOQOL-OLD) occurred at baseline(n = 36), post-intervention (n = 34), and 3-month follow-up (n = 32).

Retention was 88.9%. Significant improvements (p < .001) were observed across all measures. Effect sizes were substantial: depression reached 2.67 (post-treatment) and 2.03 (follow-up). Quality of life increased from 1.79 to 2.39. While these results are promising, the lack of a control group limits causal inferences.

The 10-week transdiagnostic group intervention integrates UP and PBT, providing a culturally adaptable framework for late-life emotional disorders. While large observed effects were noted for depression (d_z = 2.67) and quality of life (d_z = 2.39), strict caution is required due to the single-arm design. Results warrant further evaluation through randomized controlled trial.

This culturally adapted, time-limited group framework offers a scalable, resource-efficient model for comorbid older adults. It enhances treatment accessibility, fosters resilience, and reduces healthcare burden.