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Single-nucleotide variant profiling in liquid biopsy with RECO-Cas.

Chong Guo1,2, Shuo Zhang1,2, Ramachandra Yerramsetti1

  • 1Department of Biomedical Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA.

Science Advances
|May 22, 2026
PubMed
Summary

A new RECO-Cas assay detects cell-free DNA (cfDNA) mutations with high accuracy. This rapid, cost-effective liquid biopsy method aids precision oncology and early cancer diagnosis.

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