An international multidisciplinary consensus statement on laparoscopic liver biopsy.

Si-Yi Lei1, Yu Han2, Don C Rockey3

  • 1MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Cixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, China.

Summary

Laparoscopic liver biopsy is a method to collect liver tissue samples using a visual approach. It is used in complex or high-risk cases where traditional percutaneous biopsy may not be suitable. Clinical practices for this procedure vary globally due to the lack of standardized guidelines. To address this, a group of 45 international experts from multiple disciplines developed a consensus using a structured Delphi process. The statement covers when to use laparoscopic biopsy, how to prepare for it, the surgical steps, and how to manage complications. The authors suggest that this guidance may help standardize the procedure, improve safety, and support its appropriate use in complex cases. The consensus aims to promote better diagnostic outcomes and consistent clinical practice.

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