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Keep it Simple, Stupid! Towards PySTRIPA for Medication Reviews.
Marco Spruit1,2
1Leiden University Medical Center (LUMC), The Netherlands.
Studies in Health Technology and Informatics
|May 23, 2026
Summary
PySTRIPA, a reimagined Systematic Tool to Reduce Inappropriate Prescribing Assistant (STRIPA), enhances medication review for polypharmacy patients. This Python-based system offers a more maintainable and clinically usable solution.
Area of Science:
- * Health Informatics
- * Clinical Pharmacy
- * Software Engineering
Background:
- * Polypharmacy presents a significant challenge in patient care, increasing the risk of inappropriate prescribing.
- * Existing medication review systems may suffer from legacy technology dependencies, hindering maintainability and deployment.
- * The Systematic Tool to Reduce Inappropriate Prescribing Assistant (STRIPA) is a medication review system at Technology Readiness Level 7 (TRL7).
Purpose of the Study:
- * To reimagine and refactor the STRIPA medication review system into a Python-only implementation, named PySTRIPA.
- * To remove legacy technology dependencies from the core backend component of STRIPA.
- * To create a more maintainable, distributable, and clinically usable medication review system.
Main Methods:
- * Gathering user, functional, and non-functional requirements for the PySTRIPA prototype.
- * Developing the PySTRIPA prototype from scratch in Python based on gathered requirements.
- * Illustrating the PySTRIPA prototype's functionality using a clinically relevant patient use case.
- * Evaluating the PySTRIPA prototype with senior General Practitioners (GPs) using multiple patient cases.
Main Results:
- * Successful development of the PySTRIPA prototype in Python, meeting newly defined requirements.
- * Positive reception and enthusiasm from senior GPs during prototype evaluation.
- * Demonstrated viability of the PySTRIPA prototype for analyzing clinically relevant patient cases.
Conclusions:
- * The PySTRIPA prototype confirms the viability of an agile roadmap for enhancing STRIPA.
- * The refactored system is more maintainable, distributable, and clinically usable.
- * PySTRIPA represents a significant step towards an improved medication review system at TRL7+.
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