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Toward Interoperable Variable Definitions: A FHIR-Based Standardization Strategy for the METASTRA Project

Serena Moscato1,2, Alberto Marfoglia3, Valerio Antonio Arcobelli1

  • 1Department of Electrical, Electronic, and Information Engineering - Guglielmo Marconi (DEI), University of Bologna, Bologna, Italy.

Studies in Health Technology and Informatics
|May 23, 2026
PubMed
Summary

Standardizing multicenter clinical data using Health Level Seven Fast Healthcare Interoperability Resources (HL7 FHIR) and SNOMED CT improves research quality. This approach successfully standardized 88% of variables, enhancing data reuse for personalized vertebral metastasis strategies.

Keywords:
FHIRInteroperabilitySNOMED-CT

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