Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Outliers and Influential Points01:08

Outliers and Influential Points

An outlier is an observation of data that does not fit the rest of the data. It is sometimes called an extreme value. When you graph an outlier, it will appear not to fit the pattern of the graph. Some outliers are due to mistakes (for example, writing down 50 instead of 500), while others may indicate that something unusual is happening. Outliers are present far from the least squares line in the vertical direction. They have large "errors," where the "error" or residual is the vertical...
Unusual Results01:16

Unusual Results

Unusual results are those that have a very low chance of occurring. Unusual results can be identified using probabilities and the range rule of thumb. In problems involving probability, unusual results can be observed in 2 instances – an unusually high number of successes or an unusually low number of successes.
According to the range rule of thumb, any value above or below two standard deviations, 2σ  from the mean, μ  is considered unusual.
Maximum unusual value = μ + 2σ
Minimum unusual value...
What Are Outliers?01:12

What Are Outliers?

Outliers are observed data points that are far from the least squares line. They have unusual values and need to be examined carefully. Though an outlier may result from erroneous data, at other times, it may hold valuable information about the population under study and should be included in the data. Hence, it is crucial to examine what causes a data point to be an outlier.
The z score is used to find outliers or unusual values. It should be noted that any values beyond -2 and +2 are...
Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
Hindsight Biases01:12

Hindsight Biases

Hindsight bias leads you to believe that the event you just experienced was predictable, even though it really wasn’t. In other words, you knew all along that things would turn out the way they did. Can you relate this to the phrase "Hindsight is 20/20" now?
Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This number is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 2026 Richard Perham Prize winner: Angela M. Gronenborn.

The FEBS journal·2026
Same author

Research highlights.

The FEBS journal·2026
Same author

Molecular Microbiology: celebrating bugs, drugs and biochem.

The FEBS journal·2026
Same author

Research Highlights: Hidden gems.

The FEBS journal·2026
Same author

In conversation with Karen Vousden.

The FEBS journal·2026
Same author

Research highlights: Hidden gems.

The FEBS journal·2026
Same journal

A lipid-sensitive food choice behavior influences aging outcomes from a longevity-promoting diet.

The FEBS journal·2026
Same journal

The interaction network of a rice seed-specific transcription factor OsMADS29 and the calcium sensors, calmodulin, and calmodulin-like proteins.

The FEBS journal·2026
Same journal

A large family of unusual voltage-sensing proton channels (Hv3) in mollusks.

The FEBS journal·2026
Same journal

RVB-1 and RVB-2 are stress responsive proteins in Neurospora crassa and RVB-1 interacts with the centromeric Shugoshin (SGO-1) protein.

The FEBS journal·2026
Same journal

Human APOBEC3G suppresses homologous recombination and LIG4-independent end joining in DNA double-strand break repair.

The FEBS journal·2026
Same journal

Nephronophthisis: Current clinical spectrum and molecular pathogenesis.

The FEBS journal·2026
See all related articles

Related Experiment Video

Updated: May 24, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
03:08

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

Published on: October 3, 2025

Research highlights: Hidden gems.

Yeliz Yilmaz1, Hajrah Khawaja1, Julija Hmeljak1

  • 1Federation of European Biochemical Societies, The FEBS Journal, Cambridge, UK.

The FEBS Journal
|May 23, 2026
PubMed
Summary
This summary is machine-generated.

Explore 2024 molecular life science research in The FEBS Journal, revealing novel protein functions and hidden biological roles. Discover groundbreaking studies and their significant impact on the field.

Keywords:
PGC1αParkinson's diseaseautophagychemotaxishaematopoiesisnuclear laminviral infection

More Related Videos

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Related Experiment Videos

Last Updated: May 24, 2026

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization
03:08

Using Human Differentially Expressed Gene Lists to Perform Downstream Pathway Enrichment Analysis and Target Prioritization

Published on: October 3, 2025

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
07:50

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study

Published on: April 18, 2025

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Area of Science:

  • Molecular life sciences
  • Biochemistry
  • Cell biology

Background:

  • The FEBS Journal publishes cutting-edge research in molecular life sciences.
  • Understanding protein function is crucial for biological insights.

Purpose of the Study:

  • To highlight significant original research published in The FEBS Journal in 2024.
  • To showcase studies uncovering noncanonical protein functions and previously unknown roles.

Main Methods:

  • Review of original research articles published in The FEBS Journal in 2024.
  • Identification of studies focusing on protein function and biological roles.

Main Results:

  • A collection of outstanding studies spanning diverse molecular life science topics.
  • Research revealing noncanonical functions of selected proteins.
  • Studies exposing previously hidden roles of biological molecules.

Conclusions:

  • The highlighted research offers valuable insights into molecular life sciences.
  • These studies present opportunities to revisit and appreciate significant scientific discoveries.