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Updated: May 25, 2026

The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time
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The Role of Program Implementation Quality in Family-Focused Substance-Use Prevention for Youth with Multiple Risks:

Yoon S Hur1, Sarah M Chilenski2, Patrick R O'Neill2

  • 1Edna Bennett Pierce Prevention Research Center, Pennsylvania State University, University Park, PA, USA. yph5180@psu.edu.

Prevention Science : the Official Journal of the Society for Prevention Research
|May 23, 2026
PubMed
Summary
This summary is machine-generated.

High-quality implementation of evidence-based prevention programs for adolescents significantly reduces substance use, especially for those at higher risk. Effective facilitation and participant engagement are key factors in program success.

Keywords:
AdherenceFacilitation qualityFidelityImplementation qualityParticipant responsivenessSubstance-use preventionYouth with risks

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Area of Science:

  • Adolescent Health
  • Substance Abuse Prevention
  • Implementation Science

Background:

  • Adolescent substance use is a significant public health concern with long-term consequences.
  • Early intervention programs aim to build youth skills and delay substance experimentation.
  • Effective program delivery is crucial, particularly for high-risk adolescents.

Purpose of the Study:

  • To examine the impact of implementation outcomes of family-focused, evidence-based prevention programming.
  • To assess how implementation quality influences substance use in adolescents based on initial risk levels.
  • To determine if community-level implementation quality moderates the link between baseline risk and later substance use.

Main Methods:

  • Multi-level analysis of data from two cohorts across 14 school districts.
  • Assessment of three implementation outcomes: adherence, facilitation quality, and participant responsiveness.
  • Examination of the relationship between baseline risk, implementation quality, and ninth-grade substance use.

Main Results:

  • Higher implementation quality, especially facilitation quality and participant responsiveness, correlated with lower adolescent substance use.
  • High implementation quality was significantly linked to lower substance initiation index scores in high-risk youth.
  • Similar positive effects were observed for the initiation of marijuana, cigarette, and alcohol use.

Conclusions:

  • Effective implementation of prevention programs is critical for reducing adolescent substance use.
  • Facilitation quality and participant responsiveness are key components of successful program delivery.
  • Evidence-based prevention strategies, when well-implemented, can mitigate substance use risks in adolescents.