Related Experiment Video
Updated: May 25, 2026
Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Safety and Efficacy of Double-Effect Kissing Balloon Technique in Left Main Bifurcation Percutaneous Coronary
Takayuki Warisawa1,2, Shuhei Odagiri3, Masanobu Ishii4,5
1Department of Cardiovascular Medicine, Kitasato University Hospital, Sagamihara, Japan, warisawa-tky@umin.ac.jp.
Introduction:
The Japanese Coronary Intervention Using Drug-Eluting and Perfusion Therapy for Left Main Disease Registry (JDEPTH-LM Registry) is a prospective, multicenter observational study in 32 Japanese institutions evaluating the double-effect kissing balloon technique (W-KBT) as a novel strategy for left main trunk percutaneous coronary intervention (LM-PCI). This approach combines provisional crossover stenting, proximal optimization technique, KBT, and prolonged (≥30 s) KBT using a perfusion balloon for the left anterior descending artery and a drug-coated balloon for the left circumflex (LCx) ostium.
Methods:
A total of 280 patients with stable/unstable angina or non-ST-elevation myocardial infarction and LCx ostial involvement will be enrolled. The co-primary endpoints are procedural success and major adverse cardiovascular events at 12 months. The JDEPTH-LM Registry will provide clinical data on the safety and efficacy of W-KBT, which may enhance outcomes in LM-PCI involving the LCx ostial lesion.
Conclusion:
These findings could contribute to the optimization of complex LM-PCI strategies in clinical practice.
