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Updated: May 26, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
Published on: September 18, 2013
True Hemothorax as the Initial Presentation of Prostate Adenocarcinoma with Pleural Metastasis: A Case Report
Toru Kuratomi1, Shun Takao1, Maho Iwasaki1
1Department of Respiratory Medicine, Hiroshima City Hiroshima Citizens Hospital, Japan.
Abstract:
True hemothorax as an initial manifestation of prostate cancer has not yet been reported. An adult male presented with acute right-sided pleural effusion. Diagnostic thoracentesis yielded hemorrhagic pleural fluid, with a pleural fluid hematocrit ≥ 50% of the peripheral blood hematocrit, confirming hemothorax. Contrast-enhanced computed tomography revealed prostate enlargement, pulmonary nodules, and pleural masses. Transbronchial biopsies of the pulmonary nodule confirmed metastatic adenocarcinoma positive for prostate-specific antigen and negative for thyroid transcription factor-1, thus establishing the diagnosis of metastatic prostate adenocarcinoma. Androgen deprivation therapy improved the hemothorax. Bloody pleural effusion warrants hematocrit measurement and evaluation for malignancy, including metastatic prostate cancer.
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