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Rapid Recovery Following Early Immunotherapy in Acute Necrotizing Encephalopathy of Childhood

Apoorv Saxena1, Mithun Krishna Sb1, Nandini Kaul1

  • 1Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Indian Journal of Pediatrics
|May 24, 2026
PubMed
Abstract

No abstract available in PubMed .

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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...