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Published on: September 26, 2018

Temporal Trends and Forecasted Cardiac Arrest and Hypertension-Related Mortality in U.S. Adults, 2000-2035: A

Saifullah Khan1, Fnu Arsheen1, Muneeb Fareed1

  • 1Department of Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.

Journal of Epidemiology and Global Health
|May 24, 2026
PubMed

Insights

Cardiac arrest with hypertension causes significant and increasing deaths in the U.S. Targeted public health interventions are crucial to address disparities in mortality rates.

Area of Science:

  • Cardiovascular Disease Epidemiology
  • Public Health Surveillance
  • Geriatric Cardiology

Background:

  • Hypertension (HTN) and cardiac arrest (CA) intersection is a critical U.S. health issue.
  • Combined conditions may worsen outcomes and exacerbate existing disparities.
  • This study analyzes national trends and projects future mortality.

Purpose of the Study:

  • Characterize national trends in CA with concurrent HTN (2000-2024).
  • Project age-adjusted mortality rates (AAMRs) through 2035.
  • Identify demographic and geographic disparities in CA mortality.

Main Methods:

  • Retrospective analysis of CDC WONDER database (adults ≥25 years).
  • Calculated AAMRs and used joinpoint regression for trend analysis.
  • Employed Auto-ARIMA and Prophet models for mortality projections.

Main Results:

  • 1,693,840 deaths from CA with HTN (2000-2024).
  • Overall AAMR increased from 24.56 to 31.68 (AAPC 0.82).
  • Highest burden observed in men, non-Hispanic Black adults, older adults, and the West region.

Conclusions:

  • CA with HTN presents a substantial and growing mortality burden.
  • Significant demographic and geographic disparities persist.
  • Continued surveillance and targeted interventions are essential.
Abstract

Keywords:
Cardiac arrestCardiovascular mortalityForecastingHypertensionMortality trendsTemporal trends

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