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Related Concept Videos

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: May 26, 2026

Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment
11:00

Visualization, Quantification, and Mapping of Immune Cell Populations in the Tumor Microenvironment

Published on: March 25, 2020

[Interpreting the Tumor Microenvironment via Spatial Transcriptomics - Pathology Imaging and Cell-Cell Interactions].

Yukina Kusunoki1, Shugo Suzuki, Kanae Echizen

  • 1Dept. of Pathophysiology, Osaka Metropolitan University, Graduate School of Medicine.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|May 25, 2026
PubMed
Summary

Spatial transcriptomics integrates gene expression with tissue location, revolutionizing histopathology. This technology analyzes cell interactions and dynamic changes in the tumor microenvironment (TME) for improved patient stratification.

Area of Science:

  • Molecular Biology
  • Genomics
  • Biotechnology

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