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Maternal Adverse Childhood Experiences (ACEs), Resilience, Paternal Social Health, Infant Developmental Milestone
Lily Zheng1, Hsiao-Wei Banks2, Krystal Hunter3
1Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ USA.
Insights
Parental drug use, particularly paternal marijuana use, impacts infant developmental milestones. Maternal resilience is crucial, as lower resilience correlates with delayed infant development, while maternal ACEs showed no direct association.
Area of Science:
- Perinatal Health
- Child Development
- Maternal Mental Health
Background:
- Maternal risk factors like adverse childhood experiences (ACEs) and parental drug use affect offspring health.
- Maternal resilience can mitigate these risks, but their combined impact on infant developmental milestones (DM) is understudied.
Purpose of the Study:
- To investigate the association between maternal ACEs, maternal resiliency, and parental social history on infant DM achievement in the first year of life.
Main Methods:
- 107 mother-infant pairs were studied between 2020-2022.
- Maternal ACEs, resilience (7C's Tool), and paternal drug history were assessed.
- Infant DM (motor, social, language, cognitive) were tracked at 2, 4, 6, and 12 months.
Main Results:
- Paternal marijuana use was linked to decreased odds of DM achievement at 2 months.
- Lower maternal resilience (higher 7C's Tool score) correlated with lower odds of meeting all DM by 4 months.
- Paternal cannabis use was associated with increased odds of meeting all DM by 4 months; no significant association found between maternal ACEs and infant DM.
Conclusions:
- Paternal marijuana use and maternal resilience significantly influence infant developmental milestones.
- While maternal ACEs did not show a direct link, parental substance use and maternal resilience are key factors in early child development.
Abstract:
Maternal risk factors, such as adverse childhood experiences (ACEs), and a parental history of drug use negatively impact offspring health. Maternal resiliency mitigates these risks. However, the interplay and impact of these factors on infant developmental milestones (DM) achievement during the first year of life is understudied. To investigate the association between maternal ACEs, maternal resiliency, and parental social history on infant developmental milestones (DM) achievement. 107 mother-infant pairs from a New Jersey urban tertiary level academic hospital Jersey between 2020 and 2022. Participants were approached between their 2nd trimester of pregnancy and infants' 2-month well visit. Maternal health and paternal history of drug use were assessed. Mothers completed the 7C's Tool survey and Adverse Childhood Experience Questionnaire. Infant DM achievement, including motor, social, language, and cognitive DM, were collected at 2-, 4-, 6-, and 12-months well-visits. A logistic regression model analyzed relationships between maternal ACE scores and resilience, paternal health factors, and infant DM achievement. Paternal marijuana use decreased the odds of DM achievement at 2- months (p=0.003), and social/emotional DM achievement at 2-months (p=0.005). Paternal mental health challenges have lower odds of meeting all DM achievement at 4- months (p=0.043). For every unit increase in 7C's Tool survey, with higher increase reflecting lower maternal resilience, there were lower odds of meeting all DM within 4 months (p=0.044). Paternal use of cannabis increases the odds of a child meeting all DM at 4 months (p=0.042). There was no significant association between infant DM and maternal ACEs. Our findings support growing evidence that maternal ACEs and paternal marijuana use influence infant development. Future studies should explore the influence of maternal ACEs and parental drug use on neonatal outcomes.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s40653-025-00768-0.
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