Related Experiment Video
Updated: May 26, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Psychological Mechanisms of Negative Life Events on Depressed Mood in Adolescents: A Network and Moderated Mediation
Yiyi Wang1, Yalin Chen1, Zhebin Shen1
1Faculty of Psychology, Southwest University, No.2 Tiansheng Road, Beibei District, Chongqing, P. R. China.
Abstract:
The influence of negative life events (NLE) on adolescents' depressed mood is well established. However, the underlying psychological mechanisms remain unclear. This study examined the psychological mechanisms linking NLE to depressed mood, with a focus on childhood trauma (CT) and recent negative life events (RNLE). A total of 1,164 high-school students participated in the survey, and network analysis was used to examine relationships among CT, RNLE, and depressed mood. Additionally, mediation analyses examined the roles of experience of pleasure (EP) and maladaptive cognitive emotion regulation (MCER), and the moderating effect of resilience was also tested. Network analysis indicated that emotional abuse and interpersonal stress occupied central positions in the network. Furthermore, EP and MCER significantly mediated the associations between negative life events and depressed mood, and resilience moderated the links among NLE, EP, MCER, and depressed mood. By integrating network analysis with moderated mediation modeling, the study clarifies the pathways through which different types of NLE affect depressed mood in adolescents and highlights the potential of interventions that enhance cognitive emotion regulation and resilience. Specifically, enhancing adolescents' cognitive emotion regulation and resilience may help mitigate the impact of negative life events on depression.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s40653-025-00805-y.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Bullying
Psychological Responses to Stress
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

