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Updated: May 26, 2026
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Published on: October 29, 2014
Association between nutritional status at admission and inadequate bowel preparation in inflammatory bowel disease
Fangxin Wei1, Hongli Liu1, Xiaomei Song1
1Department of Gastroenterology, Chongqing General Hospital, Chongqing University, Chongqing, China.
Background:
Malnutrition is highly prevalent among patients with inflammatory bowel disease (IBD). However, the relationship between nutritional status and the quality of bowel preparation in this population remains unexplored.
Aims:
This study aims to investigate the association between nutritional status at admission and inadequate bowel preparation in patients with IBD.
Methods:
This retrospective cohort study included 697 patients diagnosed with IBD at Chongqing General Hospital between 2021 and 2025. Nutritional status was comprehensively evaluated using three validated screening tools: the Prognostic Nutritional Index (PNI), the Nutritional Risk Index (NRI), and the Nutritional Risk Screening (NRS). Logistic regression analyses were performed to identify predictors of inadequate bowel preparation. Restricted cubic spline analysis was employed to examine potential nonlinear relationships, and subgroup analysis was performed to explore possible interactions. Furthermore, predictive performance was assessed and compared using receiver operating characteristic curves, net reclassification improvement, and integrated discrimination improvement.
Results:
The prevalence of malnutrition in patients with IBD, as assessed by the PNI, NRS, and NRI, was 6.3, 8.8, and 28.0%, respectively. Logistic regression analysis identified PNI, NRS, and NRI as independent risk factors for inadequate bowel preparation. Restricted cubic spline analysis revealed significant nonlinear relationships between inadequate bowel preparation and nutritional status, particularly as measured by PNI and NRI. Significant effects were observed in specific subgroups. Among the three indices, the NRI demonstrated the best predictive performance in this study.
Conclusion:
Nutritional status assessed at admission may be an independent predictor of inadequate bowel preparation in patients with inflammatory bowel disease.
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